Nanoscopic particles resist full encapsulation, Sandia simulations show

Cigar-shaped polymer-coated gold nanoparticles on a “sea” of water molecules

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Neal Singer
nsinger@sandia.gov
505-845-7078

Sandia researcher Matt Lane stands before computer simulations of 2-nm. gold particles too small to measure experimentally. The particles aggregate to produce cigar-shaped objects that prefer to sit at the water’s surface. Red represents oxygen, blue  carbon, white hydrogen, yellow the sulfur coating. The gold particles are  not modeled directly. (Photo by Randy Montoya) Click on the thumbnail for a high-res image.

Sandia researcher Matt Lane stands before computer simulations of 2-nm. gold particles too small to measure experimentally. The particles aggregate to produce cigar-shaped objects that prefer to sit at the water’s surface. Red represents oxygen, blue carbon, white hydrogen, yellow the sulfur coating. The gold particles are not modeled directly. (Photo by Randy Montoya) Click on the thumbnail for a high-res image.
Sandia researcher Matt Lane stands before computer simulations of 2-nm. gold particles too small to measure experimentally. The particles aggregate to produce cigar-shaped objects that prefer to sit at the water’s surface. Red represents oxygen, blue carbon, white hydrogen, yellow the sulfur coating. The gold particles are not modeled directly. (Photo by Randy Montoya) Click on the thumbnail for a high-res image.

Formerly unrealized defect results in clumping and unwanted chemical interactions

ALBUQUERQUE, N.M.— It may seem obvious that dunking relatively spherical objects in a sauce — blueberries in melted chocolate, say — will result in an array of completely encapsulated berries.

Relying on that concept, fabricators of spherical nanoparticles have similarly dunked their wares in protective coatings in the belief such encapsulations would prevent clumping and unwanted chemical interactions with solvents.

Unfortunately, reactions in the nanoworld are not logical extensions of the macroworld, Sandia National Laboratories researchers Matthew Lane and Gary Grest have found.

In a cover article this past summer in Physical Review Letters, the researchers use molecular dynamics simulations to show that simple coatings are incapable of fully covering each spherical nanoparticle in a set.

Instead, because the diameter of a particle may be smaller than the thickness of the coating protecting it, the curvature of the particle surface as it rapidly drops away from its attached coating provokes the formation of a series of louvres rather than a solid protective wall (see illustration).

“We’ve known for some time now that nanoparticles are special, and that ‘small is different,’” Lane said. “What we’ve shown is that this general rule for nanotechnology applies to how we coat particles, too.”

Carlos Gutierrez, manager of Sandia’s Surfaces and Interface Sciences Department, said, “It’s well-known that aggregation of nanoparticles in suspension is presently an obstacle to their commercial and industrial use. The simulations show that even coatings fully and uniformly applied to spherical nanoparticles are significantly distorted at the water-vapor interface.”

The protective capabilities of a chain-link molecular coating are lessened when, instead of attaching to a flat surface to form an unbroken wall (fig. 1), the radius of the nanoparticle is so small that the extreme surface curvatuere opens spaces between the protective molecules (fig. 2).
The protective capabilities of a chain-link molecular coating are lessened when, instead of attaching to a flat surface to form an unbroken wall (fig. 1), the radius of the nanoparticle is so small that the extreme surface curvatuere opens spaces between the protective molecules (fig. 2). (Drawing courtesy Matt Lane, Sandia National Labs) Click on the thumbnail for a high-res image.

Said Grest, “You don’t want aggregation because you want the particles to stay distributed throughout the product to achieve uniformity. If you have particles of, say, micron-size, you have to coat or electrically charge them so the particles don’t stick together. But when particles get small and the coatings become comparable in size to the particles, the shapes they form are asymmetric rather than spherical. Spherical particles keep their distance; asymmetric particles may stick to each other.”

The simulation’s finding isn’t necessarily a bad thing, for this reason: Though each particle is coated asymmetrically, the asymmetry is consistent for any given set. Said another way, all coated nanoscopic sets are asymmetric in their own way.

A predictable, identical variation occurring in every member of a nanoset could open doors to new applications.

“What we’ve done here is to put up a large ‘dead end’ sign to prevent researchers from wasting time going down the wrong path,” Lane said. “Increasing surface density of the coating or its molecular chain length isn’t going to improve patchy coatings, as it would for larger particles. But there are numerous other possible paths to new outcomes when you can control the shape of the aggregation.”

The paper, “Spontaneous Asymmetry of Coated Spherical Nanoparticles in Solution and at Liquid-Vapor Interfaces,” was published on June 9 in Physical Review Letters 104, 235501 (2010).

The computations were carried out at the New Mexico Computing Application Center. The work was supported, in part, by the Center for Integrated Nanotechnologies, a U.S. Department of Energy, Office of Basic Energy Sciences user facility and by the National Institute for NanoEngineering through Laboratory Directed Research and Development program at Sandia National Laboratories.

 

Sandia National Laboratories is a multimission laboratory operated by National Technology and Engineering Solutions of Sandia LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration. Sandia Labs has major research and development responsibilities in nuclear deterrence, global security, defense, energy technologies and economic competitiveness, with main facilities in Albuquerque, New Mexico, and Livermore, California.

Sandia news media contact

Neal Singer
nsinger@sandia.gov
505-845-7078