Bioscience / Medical Research

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Progress toward plugging an antibiotic pump
August 20, 2018 • ALBUQUERQUE, N.M. — Each year in the U.S., at least 23,000 people die from infections caused by antibiotic resistant bacteria, according to the Centers for Disease Control and Prevention. Using computer modeling, researchers from Sandia National Laboratories and the University of Illinois at Urbana-Champaign are helping to develop the means...
Categories: Bioscience / Medical Research
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Susan Rempe

Sandia researcher Jeff Brinker elected fellow of American Academy of Arts and Sciences
June 27, 2018 • ALBUQUERQUE, N.M. — Jeff Brinker, Sandia National Laboratories fellow and University of New Mexico regents’ professor, has been elected fellow of the oldest learned society and independent policy research center in the United States: the American Academy of Arts and Sciences. The academy’s 1780 charter states its purpose is “to...
Categories: Awards, Biology, Bioscience / Medical Research, Science / Technology / Engineering
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Brinker

Riding bacterium to the bank
May 17, 2018 • LIVERMORE, Calif. — What does jet fuel have in common with pantyhose and plastic soda bottles? They’re all products currently derived from petroleum. Sandia National Laboratories scientists have demonstrated a new technology based on bioengineered bacteria that could make it economically feasible to produce all three from renewable plant sources....
Categories: Bioscience / Medical Research, Renewable energy, Science / Technology / Engineering
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Magnetic nanoparticles leap from lab bench to breast cancer clinical trials
April 30, 2018 • ALBUQUERQUE, N.M. — Sandia National Laboratories materials chemist Dale Huber has been working on the challenge of making iron-based nanoparticles the exact same size for 15 years. Now, he and his long-term collaborators at Imagion Biosystems will use these magnetic nanoparticles for their first breast cancer clinical trial later this...
Categories: Bioscience / Medical Research, Nanotechnology
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Dale Huber, in a blue labcoat holds a small white microfluidic chip beside a large, basket-ball sized round-bottom flask.

Using biomimicry to detect outbreaks faster
April 9, 2018 • ALBUQUERQUE, N.M. — Our immune systems are made up of billions of white blood cells searching for signs of infections and foreign invaders, ready to raise the alarm. Sandia National Laboratories computer scientists Pat Finley and Drew Levin have been working to improve the U.S. biosurveillance system that alerts authorities...
Categories: Bioscience / Medical Research, Computing
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Pat Finley, Drew Levin, and Melanie Moses sit in an emergency room, looking at a laptop.

Glowing designer sponges: New nanoparticles engineered to image and treat cancer
February 26, 2018 • ALBUQUERQUE, N.M. — A Sandia National Laboratories team has designed and synthesized nanoparticles that glow red and are stable, useful properties for tracking cancer growth and spread. This work is the first time the intrinsic luminescence of metal-organic framework materials, or MOFs, for long-term bioimaging has been reported, materials chemist...
Categories: Bioscience / Medical Research, Nanotechnology
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Lauren Rohwer, Dorina Sava Gallis, and Kim Butler examine tubes of glowing MOF nanoparticles that they designed, synthesized, and tested.

Blast, impact simulations could lead to better understanding of injuries and body armor
January 23, 2018 • ALBUQUERQUE, N.M. — Sandia National Laboratories is developing specialized computer modeling and simulation methods to better understand how blasts on a battlefield could lead to traumatic brain injury and injuries to vital organs, like the heart and lungs. Researchers at Sandia have studied the mechanisms behind traumatic brain injury for...
Categories: Bioscience / Medical Research, Computing, Military / Defense
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Researchers at Sandia work on new way to image brain
January 18, 2018 • ALBUQUERQUE, N.M. — Sandia National Laboratories researchers want to use small magnetic sensors to image the brain in a way that’s simpler and less expensive than the magnetoencephalography system now used. Magnetoencephalography is a noninvasive way to measure tiny magnetic fields produced by the brain’s electrical activity. The measurements, able...
Categories: Bioscience / Medical Research, Science / Technology / Engineering
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Infectious diseases: CTRL + ALT + Delete
November 21, 2017 • Sandia joins gene editing safety project LIVERMORE, Calif.— Gene editing is revolutionizing the bioscience research landscape and holds great promise for “deleting” diseases from human bodies. Sandia National Laboratories is working to make this technology safer and to ensure that one day it can be delivered into humans without triggering...
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New routes to renewables: Sandia speeds transformation of biofuel waste into wealth
November 9, 2017 • LIVERMORE, Calif. — A Sandia National Laboratories-led team has demonstrated faster, more efficient ways to turn discarded plant matter into chemicals worth billions. The team’s findings could help transform the economics of making fuels and other products from domestically grown renewable sources. Lignin, the tough material left over from biofuel...
Categories: Bioscience / Medical Research, Renewable energy
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Seema Singh

Painless microneedles extract fluid for wearable sensors for soldiers, athletes
October 2, 2017 • ALBUQUERQUE, N.M. — The lab is calm and quiet, clean and well organized; boxes of tiny needles and sample tubes are neatly stacked above a pristine paper-covered countertop. This is a far cry from the hectic emergency room, dusty battlefield or sweaty training center Sandia National Laboratories and University of...
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Ronen Polsky positions a prototype 3-D-printed microneedle holder on the arm of Mollie Rappe in a lab.

Research from Sandia shows brain stimulation during training boosts performance
April 24, 2017 • ALBUQUERQUE, N.M. — Your Saturday Salsa club or Introductory Italian class might be even better for you than you thought. According to Sandia National Laboratories cognitive scientist Mike Trumbo, learning a language or an instrument or going dancing is the best way to keep your brain keen despite the ravages...
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Mike Trumbo adjusts an electrode on Laura Matzen's head

Sandia honored for fighting Ebola, analyzing emerging biotechnologies
April 20, 2017 • ALBUQUERQUE, N.M. — The work of Sandia National Laboratories at the intersection of biology and national security, including lifesaving efforts during the 2014 Ebola epidemic, has been recognized by the Department of Energy. On April 11, Dmitri Kusnezov, chief scientist and senior adviser to the secretary of energy, visited Sandia...
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Paula Austin outside an Ebola treatment unit in Sierra Leone.

New brain-inspired cybersecurity system detects ‘bad apples’ 100 times faster
March 21, 2017 • ALBUQUERQUE, N.M. — Cybersecurity is critical — for national security, corporations and private individuals. Sophisticated cybersecurity systems excel at finding “bad apples” in computer networks, but they lack the computing power to identify the threats directly. Instead, they look for general indicators of an attack; call them “apples.” Or the...
Categories: Bioscience / Medical Research, Cybersecurity
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Roger Suppona, John Naegle, and David Follett hold Neuromorphic Cyber Microscope.

Testing for Zika virus: there’s an app for that
March 20, 2017 • LIVERMORE, Calif. — Add rapid, mobile testing for Zika and other viruses to the list of things that smartphone technology is making possible. Researchers at Sandia National Laboratories have developed a smartphone-controlled, battery-operated diagnostic device that weighs under a pound, costs as little as $100 and can detect Zika, dengue...
Categories: Biology, Bioscience / Medical Research, Science / Technology / Engineering
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Zika box

Designing diagnostic labs that are safe, specific and sustainable
January 24, 2017 • ALBUQUERQUE, N.M. — An outbreak is like a wildfire; the sooner it’s caught, the easier it is to fight, said Vips Halkjaer-Knudsen, a lab design expert at Sandia National Laboratories. To detect an outbreak early — whether Ebola, Zika or influenza — healthcare workers must have a local, trustworthy diagnostic...
Categories: Bioscience / Medical Research, Homeland security
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Bill Arndt in biosafety demonstration lab

Grand Canyon rim-to-rim hikers provide data for Sandia study of health, performance
January 4, 2017 • LIVERMORE, Calif. – It takes a special type of person to hike from one rim of the Grand Canyon to the other in a single day. These motivated, resilient athletes now are helping researchers at Sandia National Laboratories and the University of New Mexico (UNM) to collect and study biometric...
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check-in

Researchers at Sandia, Northeastern develop method to study critical HIV protein
August 3, 2016 • ALBUQUERQUE, N.M. – More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today’s anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can’t eradicate the virus. Mike Kent, a researcher in Sandia National Laboratories’ Biological and...
Categories: Bioscience / Medical Research, Science / Technology / Engineering
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Mike Kent with specially designed Languir trough.

Sandia researchers discover mechanism for Rift Valley fever virus infection
June 16, 2016 • Virus uses known cancer pathway LIVERMORE, Calif. — Viruses can’t live without us — literally. As obligate parasites, viruses need a host cell to survive and grow. Scientists are exploiting this characteristic by developing therapeutics that close off pathways necessary for viral infection, essentially stopping pathogens in their tracks. Rift...
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Rift Valley fever virus

Lessons from cow eyes: The long-term impacts of studying cornea biomechanics
May 17, 2016 • ALBUQUERQUE, N.M. – Nature has had millennia to optimize biomaterials for useful properties, from lightweight strength to walking on smooth, vertical surfaces. Mother-of-pearl, spider silk, cholla wood “skeletons” and gecko feet are all good examples of nature’s brilliant materials engineering. The study of gecko feet spurred research into dry nano-adhesives,...
Categories: Bioscience / Medical Research, Materials Science, Science / Technology / Engineering
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Brad Boyce with load frame

Sandia, UCLA develop screening libraries to discover drug targets for viral infections
April 4, 2016 • LIVERMORE, Calif. — As headlines highlight the threat of viruses like Ebola and Zika, researchers at Sandia National Laboratories and the University of California Los Angeles (UCLA) have teamed up to discover and uncover the viral mechanisms of infection by creating screening libraries based on CRISPR (clustered regularly interspaced short...
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Sandia UCLA CRADA

Lighting up disease-carrying mosquitoes
March 21, 2016 • LIVERMORE, Calif. — Mosquitoes are deadly efficient at spreading disease. Despite vaccines and efforts to eradicate the pesky insects, they continue to infect humans with feared diseases like Zika virus, malaria and West Nile virus. Gaining the upper hand on mosquitoes requires speed. Their life cycle is typically two weeks...
Categories: Biology, Bioscience / Medical Research
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quasr

‘Laboratory Biorisk Management’ details safety, security methods for biosciences sites
August 25, 2015 • Sandia, international experts publish first biorisk management how-to book ALBUQUERQUE, N.M. — Recent mishaps at laboratories that mishandled potentially dangerous biological substances and the transmission of the Ebola virus in a U.S. hospital are symptoms at bioscience facilities that two Sandia National Laboratories researchers think could be prevented by implementing...
Categories: Bioscience / Medical Research, Homeland security
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Laboratory Biorisk Management book editors

Biological tools create nerve-like polymer network
August 24, 2015 • Crowdsurfing motor proteins create possible prosthetic interface ALBUQUERQUE, N.M. — Using a succession of biological mechanisms, Sandia National Laboratories researchers have created linkages of polymer nanotubes that resemble the structure of a nerve, with many out-thrust filaments poised to gather or send electrical impulses. “This is the first demonstration of...
Categories: Biology, Bioscience / Medical Research, Chemistry, Materials Science, Nanotechnology, Science / Technology / Engineering
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Sandia veterinarian helps make the world safer through livestock health and biosecurity
July 28, 2015 • ALBUQUERQUE, N.M. — Dr. Melissa Finley’s credibility was on the line as she worked, surrounded by skeptics, to save the life of a dehydrated calf in rural Afghanistan. As a woman and a foreigner she had to earn the trust of the villagers she was trying to help. “They had...
Categories: Biology, Bioscience / Medical Research, Science / Technology / Engineering
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Results 26–50 of 73